1,931 research outputs found

    Isotope-based partitioning of streamflow in the oil sands region, northern Alberta: Towards a monitoring strategy for assessing flow sources and water quality controls

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    AbstractStudy regionThis study is based on the rapidly developing Athabasca Oil Sands region, northeastern Alberta.Study focusHydrograph separation using stable isotopes of water is applied to partition streamflow sources in the Athabasca River and its tributaries. Distinct isotopic labelling of snow, rain, groundwater and surface water are applied to estimate the contribution of these sources to streamflow from analysis of multi-year records of isotopes in streamflow.New hydrological insights for the regionThe results provide new insight into runoff generation mechanisms operating in six tributaries and at four stations along the Athabasca River. Groundwater, found to be an important flow source at all stations, is the dominant component of the hydrograph in three tributaries (Steepbank R., Muskeg R., Firebag R.), accounting for 39–50% of annual streamflow. Surface water, mainly drainage from peatlands, is also found to be widely important, and dominant in three tributaries (Clearwater R., Mackay R., Ells R.), accounting for 45–81% of annual streamflow. Fairly limited contributions from direct precipitation illustrate that most snow and rain events result in indirect displacement of pre-event water by fill and spill mechanisms. Systematic shifts in regional groundwater to surface-water ratios are expected to be an important control on spatial and temporal distribution of water quality parameters and useful for evaluating the susceptibility of rivers to climate and development impacts

    Dynamic Lighting Sign System for Way-Finding by People with Low Vision

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    All Else Being Equal Be Empowered

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    The original publication is available at www.springerlink.com . Copyright Springer DOI : 10.1007/11553090_75The classical approach to using utility functions suffers from the drawback of having to design and tweak the functions on a case by case basis. Inspired by examples from the animal kingdom, social sciences and games we propose empowerment, a rather universal function, defined as the information-theoretic capacity of an agent’s actuation channel. The concept applies to any sensorimotoric apparatus. Empowerment as a measure reflects the properties of the apparatus as long as they are observable due to the coupling of sensors and actuators via the environment.Peer reviewe

    Generation of navigation graphs for indoor space

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    This article proposes a comprehensive approach to computing a navigation graph for an indoor space. It focuses on a single floor, but the work is easily extensible to multi-level spaces. The approach proceeds by using a formal model, based on the combinatorial map but enhanced with geometric and semantic information. The process is almost fully automatic, taking as input the building plans providing the geometric structure of the floors and semantics of the building, such as functions of interior spaces, portals, etc. One of the novel aspects in this work was the use of combinatorial maps and their duals to provide a compact formal description of the topology and connectivity of the indoor structure represented by a connected, embedded graph. While making use of existing libraries for the more routine computational geometry involved, the research develops several new algorithms, including one for computing the local kernel of a region. The process is evaluated by means of a case study using part of a university building

    The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

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    Staphylococcus aureus is a major human pathogen causing multiple pathologies, from cutaneous lesions to life-threatening sepsis. Although neutrophils contribute to immunity against S. aureus, multiple lines of evidence suggest that these phagocytes can provide an intracellular niche for staphylococcal dissemination. However, the mechanism of neutrophil subversion by intracellular S. aureus remains unknown. Targeting of intracellular pathogens by macroautophagy/autophagy is recognized as an important component of host innate immunity, but whether autophagy is beneficial or detrimental to S. aureus-infected hosts remains controversial. Here, using larval zebrafish, we showed that the autophagy marker Lc3 rapidly decorates S. aureus following engulfment by macrophages and neutrophils. Upon phagocytosis by neutrophils, Lc3-positive, non-acidified spacious phagosomes are formed. This response is dependent on phagocyte NADPH oxidase as both cyba/p22phox knockdown and diphenyleneiodonium (DPI) treatment inhibited Lc3 decoration of phagosomes. Importantly, NADPH oxidase inhibition diverted neutrophil S. aureus processing into tight acidified vesicles, which resulted in increased host resistance to the infection. Some intracellular bacteria within neutrophils were also tagged by Sqstm1/p62-GFP fusion protein and loss of Sqstm1 impaired host defense. Together, we have shown that intracellular handling of S. aureus by neutrophils is best explained by Lc3-associated phagocytosis (LAP), which appears to provide an intracellular niche for bacterial pathogenesis, while the selective autophagy receptor Sqstm1 is host-protective. The antagonistic roles of LAP and Sqstm1-mediated pathways in S. aureus-infected neutrophils may explain the conflicting reports relating to anti-staphylococcal autophagy and provide new insights for therapeutic strategies against antimicrobial-resistant Staphylococci

    A New AR Interaction Paradigm for Collaborative TeleAssistance system: The P.O.A

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    International audienceIn this paper, we propose a prototype of a collaborative teleassistance system for mechanical repairs based on Augmented Reality (AR). This technology is generally used to implement specific assistance applications for users, which consist of providing all the information, known as augmentations, required to perform a task. For teletransmission applications, operators are equipped with a wearable computer and a technical support expert can accurately visualize what the operator sees thanks to the teletransmission of the corresponding video stream. Within the framework of remote communication, our aim is to foster collaboration, especially informal collaboration, between the operator and the expert in order to make teleassistance easier and more efficient. To do this we rely on classical repair technologies and on collaborative systems to introduce a new human-machine interaction: the Picking Outlining Adding interaction (POA interaction). With this new interaction paradigm, technical information is provided by directly Picking, Outlining and Adding information to an item in an operator's video stream

    Against `Realism'

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    We examine the prevalent use of the phrase ``local realism'' in the context of Bell's Theorem and associated experiments, with a focus on the question: what exactly is the ``realism'' in ``local realism'' supposed to mean? Carefully surveying several possible meanings, we argue that all of them are flawed in one way or another as attempts to point out a second premise (in addition to locality) on which the Bell inequalities rest, and (hence) which might be rejected in the face of empirical data violating the inequalities. We thus suggest that this vague and abused phrase ``local realism'' should be banned from future discussions of these issues, and urge physicists to revisit the foundational questions behind Bell's Theorem
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